Substrate: Histone deacetylase 2 (Enzyme: Deacetylase)
Seq-ID: P70288 [Mus musculus]
Download:fasta csv
Interaction Network(s):
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-2568242   TAL1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
histone deacetylase activity,
transcription factor binding,
sequence-specific DNA binding transcription factor activity		 ESC/E(Z) complex,
replication fork,
cytoplasm,
heterochromatin		 hippocampus development,
transcription,
histone deacetylation,
neuron differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 394 AIPEDAVHEDSGDEDGEDPDK - 19144319
HTP
0.16
 - -
0.88
 - medium

Substrate: Histone deacetylase 2 (Enzyme: Deacetylase)
Seq-ID: Q92769 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-73394   VE7_HPV16
MINT-73396   RB_HUMAN
MINT-4054286   MYBB_HUMAN
MINT-4544944   NPM_HUMAN
MINT-7302197   BUB1B_HUMAN
MINT-7761068   SRA1_HUMAN
MINT-7971268   DLG4_RAT
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
specific transcriptional repressor activity,
transcription activator activity,
histone deacetylase activity,
enzyme binding,
transcription factor binding		 ESC/E(Z) complex,
Sin3 complex,
cytoplasm,
NuRD complex		 negative regulation of gene-specific transcription from RNA polymerase II promoter,
positive regulation of cell proliferation,
negative regulation of transcription factor activity,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
positive regulation of proteolysis,
transcription,
histone deacetylation,
positive regulation of receptor biosynthetic process,
chromatin remodeling,
negative regulation of MHC class II biosynthetic process,
positive regulation of collagen biosynthetic process,
maintenance of chromatin silencing,
negative regulation of cell cycle
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 394 AIPEDAVHEDSGDEDGEDPDK CK2_group 12082111
LTP
0.17
 MOD_CK2_1
 - -
0.88
 - medium
S 394 AIPEDAVHEDSGDEDGEDPDK CK2_alpha 12082111
LTP
0.17
 MOD_CK2_1
 - -
0.88
 - medium
S 394 AIPEDAVHEDSGDEDGEDPDK - 17081983
HTP
0.17
 MOD_CK2_1
 - -
0.88
 - medium
S 394 AIPEDAVHEDSGDEDGEDPDK - 18669648
HTP
0.17
 MOD_CK2_1
 - -
0.88
 - medium
S 407 EDGEDPDKRISIRASDKRIAC - 17287340
HTP
0.27
 - -
0.68
 - medium
S 407 EDGEDPDKRISIRASDKRIAC - 18669648
HTP
0.27
 - -
0.68
 - medium
S 422 DKRIACDEEFSDSEDEGEGGR CK2_group 12082111
LTP
0.33
 MOD_CK2_1
 - -
0.75
 - medium
S 422 DKRIACDEEFSDSEDEGEGGR - 17081983
HTP
0.33
 MOD_CK2_1
 - -
0.75
 - medium
S 422 DKRIACDEEFSDSEDEGEGGR - 17287340
HTP
0.33
 MOD_CK2_1
 - -
0.75
 - medium
S 422 DKRIACDEEFSDSEDEGEGGR - 18669648
HTP
0.33
 MOD_CK2_1
 - -
0.75
 - medium
S 424 RIACDEEFSDSEDEGEGGRRN CK2_group 12082111
LTP
0.40
 MOD_CK2_1
 - -
0.76
 - medium
S 424 RIACDEEFSDSEDEGEGGRRN - 17081983
HTP
0.40
 MOD_CK2_1
 - -
0.76
 - medium
S 424 RIACDEEFSDSEDEGEGGRRN - 17287340
HTP
0.40
 MOD_CK2_1
 - -
0.76
 - medium
S 424 RIACDEEFSDSEDEGEGGRRN - 18669648
HTP
0.40
 MOD_CK2_1
 - -
0.76
 - medium

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